Histopathology of nasal mucosa and inflammatory changes in nasal wash of symptomatic rhinitis patients

نویسندگان

  • Loreni Kovalhuk
  • Nelson Rosario Filho
  • Monica Lima
  • José Ederaldo Telles
چکیده

Methods Total nasal symptom score (TNSS), NW and turbinate biopsy specimens were obtained from 36 AR and 20 NAR patients. Atopic patients had positive skin prick test to D.pteronyssinus (35/97%) and L.perenne (18/50%) extracts from Hollister-Stier. Total and differential cell counts were evaluated by a quantitative method of nasal cytology; albumin and IL-8 concentrations were determined in the supernatant of NW. The epithelium damage and BMT were assessed on H&E-stained sections by staging system. Statistical analysis was performed by nonparametric Mann-Whitney U test for comparison between cell counts and differences in frequencies by Fisher exact test.

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2015